Bioinformatics Laboratory

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Research projects

Current  projects:

  • Bioinformatics:
    • Developing of a new simplified model for representing protein structures and folding
    • Application of a multiagents system for the simulation of protein folding.
    • Genetic algorithms for protein folding problem using the 3D-HP-side chain model
    • Differential evolution for protein folding using 2D/3D continuous models
    • Cellular automata applications in bioinformatics
    • Computational tools for analysis of genomic sequences
  • Evolutionary Computation:
    • Hybrid evolutionary algorithms for engineering problems
    • Evolution of rules for cellular automata using hybrid gene-expression programming
    • Particle swarm optimization and bee-algorithm for template matching in digital images.
  • Reconfigurable Computation:
    • Gene detection with high-performance reconfigurable hardware
    • Cellular automata evolution in FPGA
  • Medical (Health) informatics & Biomedical Engineering:
    • Ontologies and artificial intelligence techniques for evaluation of patients with neurological diseases
    • Data mining in medical databases
    • Eectrical impedance spectrometry for cancer research

Previous/concluded projects:

  • Bioinformatics:
    • Computational intelligence for phylogenetic trees contruction and protein structure prediction
    • Analysis of cancer-related mutations in genomic databases
    • Mitochondrial DNA database
    • Hybrid genetic algorithms for multiple sequence alignment
    • Multiple sequence alignment in a parallel virtual machine
    • Biomolecular sequence alignment using computational intelligence  techniques
    • Data-mining in biological datasets
    • Hardware-based (FPGA) algorithms for multiple sequence alignment, protein folding and genomic analysis
    • Classification of proteins' structural motifs by means of evolutionary computation techniques - (see PROTAM project)
    • Stochastic formal languages in bioinformatics
    • Neural networks and Hidden Markov Chains for protein classification
    • Ant colony algorithms for phylogenetic tree reconstruction
  • Evolutionary Computation:
    • Gene expression programming applied to symbolic regression and data classification.
    • Operations research techniques for optimized power substations location
    • Logistic optimization of maintenance teams for power distribution networks
    • Genetic programming for data mining of medical datasets
    • Electronic circuits synthesis using genetic programming
    • Genetic algorithms for mobile robot path optimization
  • Medical (Health) informatics:
    • Intelligent tutor for learning mechanical ventilators manoeuvres
    • A multimedia system for training in kinesiology
    • A multimidia system for teaching support on the neurological evaluation of the newborn
    • Computer system for control and follow-up of clinical research protocols in oncology
    • A computational tool for distance learning using handheld computers - application in telemedicine
  • Biomedical engineering:
    • Electronic instrumentation and digital signal processing for objective evaluation of Parkinson disease
    • Relationship between the radiant energy in phototherapy and its effect in the hiperbilirrubinemy of the newborn
    • Hardware implementation of LVQ neural networks and FFT for pattern recognition in biomedical signals
    • Computer-based variability analysis of the voice acoustic parameters in the adolescence
    • Vision-operated prostetic keyboard for a brain-computer interface
    • Simulation and synthesis of EEG signals
    • An EEG signal databank
    • EEG pattern recognition using genetic programming
    • A high-performance digital signal processing board with TMS320C54 chip
    • LVQ neural networks for pattern recognition of EEG signals related to hand movements
 

Last updated: 21-out-2005